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INDICATIONS
Allergenic extracts are indicated for skin test diagnosis and treatment (immunotherapy) of patients with seasonal and perennial allergies.

WARNING: SEVERE ALLERGIC REACTIONS

Allergenic extracts can cause severe life-threatening systemic reactions, including anaphylaxis.
Do not administer allergenic extracts to patients with severe, unstable, or uncontrollable asthma.
Intended for use only by physicians who are experienced in the administration of allergenic extracts.
Observe patients in the office for at least 30 minutes following treatment. Emergency measures and personnel trained in their use must be available immediately in the event of a life-threatening reaction.
Immunotherapy may not be suitable for patients with certain underlying medical conditions that may reduce their ability to survive a systemic allergic reaction.
Allergenic extracts may not be suitable for patients receiving medications such as beta-blockers that may make them unresponsive to epinephrine or inhaled bronchodilators.

Do not inject intravenously. Initial dose should be based on skin test reactivity.

Systemic reactions include generalized skin erythema, urticaria, pruritus, angioedema, rhinitis, wheezing, laryngeal edema, chest tightness and hypotension. Other adverse reactions include local reactions at the injection site (e.g., erythema, itching, swelling, tenderness, and pain). Additional symptoms that are not usually associated with allergy also may occur, such as nausea, emesis, abdominal cramps and diarrhea.

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